Is meditation plus standard care effective in reducing anxiety among obese individuals at the phase of weight loss maintenance?
Date of publication of the randomized controlled trial: August 2016
Design
Randomized controlled trial (RCT).
Participants
41 obese participants (mean age: 51 years; 21% male) who were participating in a weight loss program and at their post weight loss maintenance phase.
Intervention
Participants in meditation group plus standard clinical care over 8 weeks of practice weekly (1 hour per session).
Comparator
Comparison: 8-week of meditation plus standard clinical care versus standard clinical care.
Major Outcomes
Outcome 1: Anxiety severity measured by the Hamilton Anxiety Scale (HAM-A). Higher score indicates more severe anxiety.
Settings
This trial was performed in an outpatient setting.
Comparison    Meditation plus standard care versus standard care alone
Main Results
Compared to standard care alone, meditation plus standard care was significantly superior in reducing anxiety measured by HAM-A (mean difference (MD): -7.7, 95% Cl: -9.2 to -6.3).
Comparison: Meditation plus standard care versus standard care among obese participants with major depressive disorder
Outcomes No. of studies (Total number of participants) Mean score (SD)/ No. of participants Heterogeneity test ( I2) MD (95% CI) p value Overall quality of evidence*
Intervention Comparator
1 1 (41) 7.8 (2.0)/20 14.9 (3.4)/21 Not applicable as there is only 1 study. -7.7 (-9.2 to -6.3) NR Very high
Keys: SD = standard deviation; MD = mean difference; CI = confidence interval; NR = not reported.
Comparison    Meditation plus standard care versus standard care alone
Main Results
Compared to standard care alone, meditation plus standard care was significantly superior in reducing anxiety measured by HAM-A (mean difference (MD): -7.7, 95% Cl: -9.2 to -6.3).
Comparison: Meditation plus standard care versus standard care among obese participants with major depressive disorder
Outcomes 1
No. of studies (Total number of participants) 1 (41)
Mean score (SD)/ No. of participants Intervention 7.8 (2.0)/20
Comparator 14.9 (3.4)/21
MD (95% CI) -7.7 (-9.2 to -6.3)
p value NR
Overall quality of evidence* Very high
Keys: SD = standard deviation; MD = mean difference; CI = confidence interval; NR = not reported.
Conclusion
Benefits
Compared to standard care alone, 8-week of meditation plus standard care significantly reduce anxiety level in obese participants at the phase of weight loss maintenance. For outcome 1, the overall quality of evidence is very high. Further research is most unlikely to have an important impact on our confidence in this estimate of effect.
Harms
No adverse events were reported.
Link to Original Article
https://www.ncbi.nlm.nih.gov/pubmed/27912933
The synopsis is based on the following article:
Sampaio CV, Lima MG, Ladeia AM. Efficacy of Healing meditation in reducing anxiety of individuals at the phase of weight loss maintenance: A randomized blinded clinical trial. Complementary therapies in medicine. 2016 Dec 31;29:1-8.


* Interpretation of quality assessment results:
• Very low: Further research is most likely to have an important impact on our confidence in this estimate of effect.
• Low: Further research is likely to have an important impact on our confidence in this estimate of effect.
• Moderate: Further research is fairly likely to have an important impact on our confidence in this estimate of effect.
• High: Further research is unlikely to have an important impact on our confidence in this estimate of effect.
• Very high: Further research is most unlikely to have an important impact on our confidence in this estimate of effect.

Details of assessment method can be found at Chung VC, Wu XY, Ziea ET, Ng BF, Wong SY, Wu JC. Assessing internal validity of clinical evidence on effectiveness of CHinese and integrative medicine: Proposed framework for a CHinese and Integrative Medicine Evidence RAting System (CHIMERAS). European Journal of Integrative Medicine. 2015 Aug 31;7(4):332-41.